Side effects, sourced

Why Do You Get Sulfur Burps on a GLP-1?

Sulfur burps on a GLP-1 are belches that smell of rotten eggs, and the prescribing labels record the belching without describing the smell. The FDA label for Wegovy (semaglutide, Novo Nordisk) lists eructation in 7% of injection-treated adults against under 1% on placebo; the Zepbound (tirzepatide, Eli Lilly) label lists it in 4% to 5% against 1%. Both labels state the drug delays gastric emptying, which is the basis of the explanation this page offers for the odor. Below: what the labels say and do not say, the meal patterns worth logging, and the signs that belong with a prescriber rather than a food diary.

· Educational content — not medically reviewed

The short answer

Sulfur burps on a GLP-1 are belches that smell of rotten eggs, and the FDA labels record the belching, not the smell: eructation was reported by 7% of adults on Wegovy (semaglutide, Novo Nordisk) versus under 1% on placebo, and by 4% to 5% on Zepbound (tirzepatide, Eli Lilly) versus 1%. Both labels state the drug delays gastric emptying, the usual explanation offered. Severe abdominal pain or repeated vomiting belongs with a prescriber.

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Key takeaways

  • No FDA label uses the phrase sulfur burps. The label term is eructation, and it counts belching without recording how it smelled.
  • Wegovy's FDA label (revised June 2026) reports eructation in 7% of injection-treated adults versus under 1% on placebo across three 68-week trials, and notes gastrointestinal reactions were most often reported during dose escalation.
  • Zepbound's FDA label (revised August 2026) reports eructation in 4%, 5% and 5% of adults across its three maintenance doses versus 1% on placebo; Mounjaro's label (revised August 2026) reports 3.0%, 2.5% and 3.3% versus 0.4% in adults with type 2 diabetes.
  • The tirzepatide labels state that the delay in gastric emptying is largest after the first dose and diminishes over time; the rotten-egg smell itself is hydrogen sulfide, which a 2012 Frontiers in Physiology review attributes to gut bacteria working on sulfur compounds, meat being a particularly important source.
  • Persistent or severe abdominal pain, repeated vomiting, or an inability to keep fluids down are label-listed warning signs, not burping. They go to the prescriber, not the log.

The label counts belches, not smells

Eructation appears in the adverse-reaction tables of the Wegovy, Zepbound and Mounjaro FDA labels. Odour is not a trial endpoint, so the 7% and 4% to 5% figures describe how many people belched more than placebo, not how many noticed sulfur.

Slowed emptying is the stated mechanism

Each label states plainly that the drug delays gastric emptying. The Zepbound and Mounjaro labels add that the delay is largest after the first dose and diminishes over time, which is why so many people describe the burps clustering around dose day.

Sulfur comes from what bacteria are fed

The rotten-egg smell is hydrogen sulfide. The Carbonero review in Frontiers in Physiology names cysteine, taurocholic acid and mucin as efficient sulfide sources for gut bacteria, with meat a particularly important one, and lists commercial breads, dried fruit, nuts and brassica vegetables among inorganic sulfate sources.

Log the episode next to the meal and the dose

GLP-1 Tracker keeps a note beside each dose entry and logs meals, so an episode can be written against that week's injection and what was eaten. It records; it does not interpret. Free, no account, stored on the device.

What the FDA labels actually list for burping

Start with the word. Prescribing labels use eructation, the clinical term for belching, and none of the three labels checked for this page uses the phrase sulfur burps or records odor. The figures below therefore answer a narrower question than the one people search for: how often trial participants belched more than people on placebo.

The Wegovy label from Novo Nordisk, revised in June 2026 and published on DailyMed and the FDA's website, pools three 68-week placebo-controlled trials in adults with obesity or overweight. In its adverse-reaction table, eructation was reported by 7% of the 2,116 adults on Wegovy injection and by fewer than 1% of the 1,261 on placebo. In the single 68-week pediatric trial, the figures were 4% of 133 adolescents on Wegovy and 0% of 67 on placebo. The same label adds a sentence worth keeping: gastrointestinal reactions, eructation among them, "were most frequently reported during dosage escalation."

The Zepbound label from Eli Lilly, revised in August 2026, pools two placebo-controlled weight-reduction trials in adults with obesity or overweight, with or without type 2 diabetes. Eructation was reported by 4%, 5% and 5% of participants on the three maintenance doses, against 1% of the 958 on placebo. The Mounjaro label, revised August 2026, draws on a different population, 718 tirzepatide-treated adults with type 2 diabetes in two placebo-controlled trials, and lists eructation at 3.0%, 2.5% and 3.3% across the same three doses versus 0.4% on placebo.

Two cautions. The trial populations, durations and comparators differ, so the numbers are not a head-to-head between semaglutide and tirzepatide. And a label frequency is a floor, not a ceiling: a participant who belched more but never mentioned it to a study nurse is not in the table. The full label facts are in the reference entries for Wegovy, Zepbound and Mounjaro.

GLP-1 Tracker visualizes your estimated medication level over time.

Why delayed gastric emptying is the explanation usually offered

The labels are direct on mechanism. Section 12.2 of the Wegovy label states that semaglutide delays gastric emptying. The Zepbound and Mounjaro labels say the same of tirzepatide and add a detail that matters for anyone tracking symptoms: "The delay is largest after the first dose and this effect diminishes over time."

That is where the label stops. It does not explain why a belch smells of eggs, because no trial measured that. The explanation this page offers is its own inference, joining two sourced facts. First, food that sits in the stomach and upper gut for longer gives bacteria more time to work on it. Second, the rotten-egg smell is hydrogen sulfide, which gut bacteria produce from sulfur-containing compounds. A 2012 review by Carbonero and colleagues in Frontiers in Physiology describes sulfate-reducing bacteria as ubiquitous in the human intestinal mucosa and notes that organic sulfur compounds such as cysteine, taurocholic acid and mucin are a more efficient source of sulfide than inorganic sulfate, "with meat being a particularly important source."

Put together, the story is plausible: slower transit, longer fermentation, more hydrogen sulfide, and a belch that carries it upward. It is also a story, not a trial finding, and this page will not dress it up as one. What the label does support is the timing pattern people report: if the emptying delay peaks after a dose and fades, an odor that tracks the dose cycle fits the mechanism, which is exactly why dose day belongs in the log.

The food patterns people track

Because the mechanism runs through what bacteria are fed, most of the patterns people notice are dietary. None of the items below is a food to avoid on this page's authority; they are variables worth writing down so that a real pattern, if there is one, shows up in your own record.

Sulfur-rich foods come first. The Carbonero review names meat as a particularly important source of the organic sulfur compounds bacteria turn into sulfide, and lists commercial breads, dried fruits, vegetables, nuts, fermented beverages and brassica vegetables among sources of inorganic sulfate. Eggs, onions and garlic are the ones people mention most in their own notes. If the worst evenings follow a large steak or a plate of roasted broccoli, that is a pattern worth showing a pharmacist, not a verdict.

Meal size is the second variable: a stomach that empties slowly has less room, and people commonly describe a heavy meal sitting for hours before the belching starts, so portion goes in the log alongside content. Carbonation is the third. A fizzy drink adds gas that has to leave somehow, and on a slowly emptying stomach it tends to leave upward; eating quickly and swallowing air does the same. The site's guide to foods that commonly feel uncomfortable on a GLP-1 covers the wider picture of greasy, sugary and oversized meals; this page stays on the sulfur question.

None of this is a diet plan. Whether any food should change in your case is a conversation with your prescriber or a registered dietitian, who can weigh the burping against protein needs, blood sugar and everything else a web page cannot see.

When a burp is not the story: signs that need a prescriber

Belching is unpleasant and, by the label's own accounting, common. The harder job is telling it apart from the reactions the same labels put in their warnings sections, because early on they can arrive together.

The Wegovy label's section 5.6, Severe Gastrointestinal Adverse Reactions, reports severe gastrointestinal reactions in 4.1% of injection-treated adults against 0.9% on placebo, and states that Wegovy is not recommended in patients with severe gastroparesis. The Zepbound and Mounjaro labels carry the same gastroparesis statement. Section 5.2 on acute pancreatitis asks clinicians to watch for "persistent or severe abdominal pain (sometimes radiating to the back)," with or without nausea and vomiting. Section 5.3 covers acute gallbladder disease. The post-marketing section lists ileus, intestinal obstruction and severe constipation including fecal impaction as reports received since approval, at frequencies the label says it cannot reliably estimate. The acute kidney injury section ties that risk to dehydration from nausea, vomiting or diarrhea.

Read as a checklist, the following are not burping and should not wait for a pattern to emerge: abdominal pain that is severe, persistent or radiating to the back; repeated vomiting; being unable to keep fluids down; a belly that is swollen and painful rather than merely gassy; days without a bowel movement alongside pain or vomiting. Those are calls to the prescriber the same day, or to emergency services if severe. The Wegovy label also instructs patients to tell any clinician about the medication before a planned surgery or procedure involving anesthesia, because of the emptying delay.

A rotten-egg belch on its own is the thing this page is about. Even then, if it is new, frequent enough to affect meals or sleep, or arrives with heartburn that did not exist before, raise it at the next appointment; a pharmacist can usually take the call sooner.

How to log episodes against meals and dose day

A single sulfur burp tells you nothing. Two weeks of dated episodes next to what you ate and where you were in the dose cycle can tell a pharmacist quite a lot, at about ten seconds per entry.

Record four things per episode: the time, an intensity on a scale you keep fixed (one to three is enough), the last meal with a rough portion, and which day of the dose cycle it was, day one being dose day. If the label is right that the emptying delay is largest after a dose and fades, episodes should thin out towards the end of the week; if they do not, that is a useful observation in its own right. Note carbonated drinks and anything from the sulfur list separately, because those are the variables a pharmacist will ask about first.

In GLP-1 Tracker each dose entry keeps the date, the injection site and your note in one place, and meals are logged separately, so an episode can be written against that week's injection and read next to what was eaten. The walkthrough on how to log a meal on a GLP-1 covers matching the entry to the plate, logging unfinished meals, and backdating rather than skipping; the procedure in how to keep a GLP-1 symptom journal applies unchanged to the burps. Everything is kept on your device and in your private iCloud, there is no account, and the app draws no conclusions from any of it.

What two weeks of notes can and cannot tell you

After a fortnight, sort the episodes three ways: by days since dose, by meal, and by the sulfur and carbonation flags. A cluster in the two days after the injection matches the label's description of the emptying delay. A cluster after particular meals is a dietary pattern. No cluster at all is also information, because it argues against the simplest explanations.

What the log cannot do is decide anything. It cannot say whether the burping will fade, whether a food should go, or whether a dose change your prescriber is considering will help. The labels say the emptying delay diminishes over time and that gastrointestinal reactions concentrate during escalation, which is grounds for patience, not for adjusting anything yourself. Your prescriber sets the dose and schedule; your pharmacist can talk through timing and meals. The guide on preparing a summary for your doctor turns the notes into a page they can read in two minutes.

One last distinction. Nausea has its own page on this site. Sulfur burps are a different complaint with a different explanation, and they can be present without any nausea at all, so keep them as their own line in the log rather than folding them into a general stomach entry.

Frequently asked questions

What causes sulfur burps on a GLP-1?

The rotten-egg smell is hydrogen sulfide, which gut bacteria produce from sulfur-containing compounds in food. Semaglutide and tirzepatide delay gastric emptying, as their FDA labels state, so food sits longer and bacteria have more time to work on it. That is the most common explanation, and it is an inference, not a trial finding; it is consistent with the labels, but no trial has measured it directly.

Do the FDA labels for Wegovy, Zepbound or Mounjaro list sulfur burps?

No label uses that phrase. The label term is eructation, meaning belching, and odor is not recorded. Wegovy's label lists eructation in 7% of injection-treated adults versus under 1% on placebo. Zepbound's lists 4%, 5% and 5% across its three maintenance doses versus 1%. Mounjaro's lists 3.0%, 2.5% and 3.3% versus 0.4% in adults with type 2 diabetes.

Why are the burps worse on dose day?

The Zepbound and Mounjaro labels state that tirzepatide's delay in gastric emptying is largest after the first dose and diminishes over time, and the Wegovy label notes that gastrointestinal reactions were most frequently reported during dose escalation. If slower emptying drives the smell, episodes clustering in the days after an injection fits. Logging days since dose is how you check it in your own record.

Which foods are linked to sulfur burps?

A 2012 review in Frontiers in Physiology by Carbonero and colleagues names meat as a particularly important source of the organic sulfur compounds bacteria turn into sulfide, and lists commercial breads, dried fruits, vegetables, nuts, fermented beverages and brassica vegetables among sources of inorganic sulfate. Eggs, onions and garlic are commonly reported, and large meals and carbonated drinks add volume and gas on a stomach that empties slowly. None of this is a diet instruction; it is a list of things worth logging.

Do sulfur burps on a GLP-1 go away?

The labels say the gastric emptying delay diminishes over time and that gastrointestinal reactions concentrate during dose escalation, which many people read as grounds for patience. Whether that holds for you is something only your own record and your prescriber can answer. Persistent, worsening or disruptive burping belongs at your next appointment.

When are burps a warning sign rather than a nuisance?

When they arrive with symptoms the labels put in their warnings sections. Persistent or severe abdominal pain, sometimes radiating to the back, is the label's description of possible acute pancreatitis. Repeated vomiting, inability to keep fluids down, a swollen painful abdomen, or days without a bowel movement alongside pain need a prescriber the same day, or emergency services if severe. Burping alone is not on that list.

Should I stop or change my dose because of sulfur burps?

That is a decision for your prescriber, not for a web page or an app. The labels describe the emptying delay as diminishing over time, and dose changes are made by the clinician who knows your history. What you can do is keep a dated record of episodes, meals and days since dose, and bring it to the person who can act on it.

How do I track sulfur burps in GLP-1 Tracker?

Write each episode into the note attached to that week's dose entry, with the day it happened and an intensity on a fixed one-to-three scale, and keep meals logged with a rough portion. The dose entry carries its own date, so working out which day of the dose cycle an episode fell on, day one being dose day, is a matter of reading it back. The app is free, there is no account, data is stored on the device, and it never interprets what you enter.

Log the burp, the meal and the dose day together

GLP-1 Tracker keeps a note beside each dose entry and logs your meals, so a pattern shows up in your own record. Free on iPhone, no account, stored on your device.

This page is for general education only and is not medical advice, diagnosis or treatment. GLP-1 Tracker is a tracking tool, not a medical device. Always consult your healthcare provider about your medication, dosing and health decisions. Brand names are trademarks of their respective owners and are not affiliated with this app.